Subject: Omega-6 excess causes DHA deficiency
Author: TakaDate: 1 Jul
An interesting update from the HYPERLIPID Blog on the EFAs:
http://high-fat-nutrition.blogspot.com/2008/06/efa-deficiencies.html
backed by e.g.:
Am J Clin Nutr. 1982 Mar;35(3):617-23.
A case of human linolenic acid deficiency involving neurological
abnormalities.
Holman RT, Johnson SB, Hatch TF.
A 6-yr-old girl who lost 300 cm of intestine was maintained by total
parenteral nutrition. After 5 months on a preparation rich in linoleic
acid but low in linolenic acid she experienced episodes of numbness,
paresthesia, weakness, inability to walk, pain in the legs, and
blurring of vision. Diagnostic analysis of fatty acids of serum lipids
revealed marginal linoleate deficiency and significant deficiency of
linolenate. When the regimen was changed to emulsion containing
linolenic acid neurological symptoms disappeared. Analysis indicated
that linoleate deficiency had worsened but linolenate deficiency had
been corrected. The requirement for linolenic acid is estimated to be
about 0.54% of calories.
PMID: 6801965
Taka
MattLB
